Posted: March 30th, 2008, 5:30am CEST
I must confess, I stole the title from a post at Genetic Future, but I think I’ll get away with it since I just linked to the original post ;-) In this post, Daniel MacArthur discusses genome wide (SNP) association mapping studies and concludes that: The fact remains that despite the hundreds of millions of dollars spent on genome-wide association studies, most of the genetic variance in risk for most common diseases remains undiscovered. He then lists a number of reasons why we have problem